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Molecular mechanism of activation of the immunoregulatory amidase NAAA

Palmitoylethanolamide is a bioactive lipid that strongly alleviates pain and inflammation in animal models and in humans. Its signaling activity is terminated through degradation by N-acylethanolamine acid amidase (NAAA), a cysteine hydrolase expressed at high levels in immune cells. Pharmacological...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gorelik, Alexei, Gebai, Ahmad, Illes, Katalin, Piomelli, Daniele, Nagar, Bhushan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205464/
https://ncbi.nlm.nih.gov/pubmed/30301806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811759115
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