Lysyl-tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis

Lysyl-tRNA synthetase (KRS) functions canonically in cytosolic translational processes. However, KRS is highly expressed in colon cancer, and localizes to distinct cellular compartments upon phosphorylations (i.e., the plasma membranes after T52 phosphorylation and the nucleus after S207 phosphoryla...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Nam, Seo Hee, Kim, Doyeun, Lee, Doohyung, Lee, Hye-Mi, Song, Dae-Geun, Jung, Jae Woo, Kim, Ji Eon, Kim, Hye-Jin, Kwon, Nam Hoon, Jo, Eun-Kyeong, Kim, Sunghoon, Lee, Jung Weon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205414/
https://ncbi.nlm.nih.gov/pubmed/30188867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99806
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