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Lysyl-tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis
Lysyl-tRNA synthetase (KRS) functions canonically in cytosolic translational processes. However, KRS is highly expressed in colon cancer, and localizes to distinct cellular compartments upon phosphorylations (i.e., the plasma membranes after T52 phosphorylation and the nucleus after S207 phosphoryla...
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| Vydáno v: | J Clin Invest |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205414/ https://ncbi.nlm.nih.gov/pubmed/30188867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99806 |
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