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Endo and Exo Diels-Alder Adducts: Temperature-Tunable Building Blocks for Selective Chemical Functionalization

The development and application of a novel endo furan-protected maleimide building block is reported. The endo isomer undergoes deprotection at temperatures ~50 °C below the exo derivative. This enables a simple and powerful approach to quantitatively and selectively introduce functional maleimide g...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Discekici, Emre H., Amant, Andre H. St., Nguyen, Shay N., Lee, In-Hwan, Hawker, Craig J., de Alaniz, Javier Read
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205238/
https://ncbi.nlm.nih.gov/pubmed/29613783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b01544
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