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PD-L1 blockade enhances anti-tumor efficacy of NK cells

Anti-PD-1/anti-PD-L1 therapies have shown success in cancer treatment but responses are limited to ~ 15% of patients with lymphocyte infiltrated, PD-L1 positive tumors. Hence, strategies that increase PD-L1 expression and tumor infiltration should make more patients eligible for PD-1/PD-L1 blockade...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Oyer, Jeremiah L., Gitto, Sarah B., Altomare, Deborah A., Copik, Alicja J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205063/
https://ncbi.nlm.nih.gov/pubmed/30377572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1509819
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