PD-1 blockade enhances elotuzumab efficacy in mouse tumor models

Elotuzumab, a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7) on myeloma cells, was developed to treat patients with multiple myeloma (MM). Elotuzumab has a dual mechanism of action that includes the direct activation of natural killer (NK) cells...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Bezman, Natalie A., Jhatakia, Amy, Kearney, Alper Y., Brender, Ty, Maurer, Mark, Henning, Karla, Jenkins, Misty R., Rogers, Amy J., Neeson, Paul J., Korman, Alan J., Robbins, Michael D., Graziano, Robert F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728054/
https://ncbi.nlm.nih.gov/pubmed/29296719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017004382
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