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WW domain–mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex

The Nedd4 family E3 ligases Itch and WWP1/2 play crucial roles in the regulation of cell cycle progression and apoptosis and are closely correlated with cancer development and metastasis. It has been recently shown that the ligase activities of Itch and WWP1/2 are tightly regulated, with the HECT do...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Yao, Weiyi, Shan, Zelin, Gu, Aihong, Fu, Minjie, Shi, Zhifeng, Wen, Wenyu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204921/
https://ncbi.nlm.nih.gov/pubmed/30213861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003781
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