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WW domain–mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex
The Nedd4 family E3 ligases Itch and WWP1/2 play crucial roles in the regulation of cell cycle progression and apoptosis and are closely correlated with cancer development and metastasis. It has been recently shown that the ligase activities of Itch and WWP1/2 are tightly regulated, with the HECT do...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204921/ https://ncbi.nlm.nih.gov/pubmed/30213861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003781 |
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