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WW domain–mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex
The Nedd4 family E3 ligases Itch and WWP1/2 play crucial roles in the regulation of cell cycle progression and apoptosis and are closely correlated with cancer development and metastasis. It has been recently shown that the ligase activities of Itch and WWP1/2 are tightly regulated, with the HECT do...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204921/ https://ncbi.nlm.nih.gov/pubmed/30213861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003781 |
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