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Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

WW domains target proline-tyrosine (PY) motifs and frequently function as tandem pairs. When studied in isolation, single WW domains are notably promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions. Here, we show that the fourth WW domain (WW4) of Suppresso...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jennings, Martin D., Blankley, Richard T., Baron, Martin, Golovanov, Alexander P., Avis, Johanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244684/
https://ncbi.nlm.nih.gov/pubmed/17656366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703453200
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