Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST)

The RE1-silencing transcription factor (REST) is the major scaffold protein for assembly of neuronal gene silencing complexes that suppress gene transcription through regulating the surrounding chromatin structure. REST represses neuronal gene expression in stem cells and non-neuronal cells, but it...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Burkholder, Nathaniel Tate, Mayfield, Joshua E., Yu, Xiaohua, Irani, Seema, Arce, Daniel K., Jiang, Faqin, Matthews, Wendy L., Xue, Yuanchao, Zhang, Yan Jessie
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204920/
https://ncbi.nlm.nih.gov/pubmed/30217818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004722
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