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Entrectinib and other ALK/TRK inhibitors for the treatment of neuroblastoma
RTK plays important roles in many cellular signaling processes involved in cancer growth and development. ALK, TRKA, TRKB, TRKC, and ROS1 are RTKs involved in several canonical pathways related to oncogenesis. These proteins can be genetically altered in malignancies, leading to receptor activation...
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| Publicat a: | Drug Des Devel Ther |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove Medical Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204873/ https://ncbi.nlm.nih.gov/pubmed/30425456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S147384 |
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