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Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on‐target ALK inhibitors in neuroblastoma
Targeted inhibition of anaplastic lymphoma kinase (ALK) is a successful approach for the treatment of many ALK‐aberrant malignancies; however, the presence of resistant mutations necessitates both the development of more potent compounds and pharmacodynamic methods with which to determine their effi...
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| Veröffentlicht in: | Mol Oncol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537911/ https://ncbi.nlm.nih.gov/pubmed/28432815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12069 |
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