Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cells

Neuroblastoma (NB) is a threatening childhood malignancy. Its prognosis is affected by several morphological, and biological characteristics, including the constitutive expression of ALK tyrosine kinase. In this study we examined the therapeutic potential of a novel ALK inhibitor, entrectinib, in ob...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Aveic, Sanja, Pantile, Marcella, Seydel, Anke, Esposito, Maria Rosaria, Zanon, Carlo, Li, Gary, Tonini, Gian Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868711/
https://ncbi.nlm.nih.gov/pubmed/26735175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6778
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