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Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation

BACKGROUND: Titanium dioxide nanoparticles (TiO(2) NPs) represent a scientific breakthrough in the areas of biological and medicinal applications. Interaction of TiO(2) NPs with components of innate immune system remains elusive. AIM: This study explored in vitro immunotoxicity of murine macrophage...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Dhupal, Madhusmita, Oh, Jae-Min, Tripathy, Dipti Ranjan, Kim, Soo-Ki, Koh, Sang Baek, Park, Kyu-Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204851/
https://ncbi.nlm.nih.gov/pubmed/30425486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S176087
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