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Flavonoids from Engineered Tomatoes Inhibit Gut Barrier Pro-inflammatory Cytokines and Chemokines, via SAPK/JNK and p38 MAPK Pathways

Flavonoids are a diverse group of plant secondary metabolites, known to reduce inflammatory bowel disease symptoms. How they achieve this is largely unknown. Our study focuses on the gut epithelium as it receives high topological doses of dietary constituents, maintains gut homeostasis, and orchestr...

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Detalhes bibliográficos
Publicado no:Front Nutr
Main Authors: Tomlinson, Matthew L., Butelli, Eugenio, Martin, Cathie, Carding, Simon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741681/
https://ncbi.nlm.nih.gov/pubmed/29326940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnut.2017.00061
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