Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway

Humanin (HN) is a novel 24-amino acid peptide that protects neurons against N-methyl-d-aspartate (NMDA)-induced toxicity. However, the contribution of the different mitogen-activated protein kinases (MAPKs) signals to HN neuroprotection against NMDA neurotoxicity remains unclear. The present study w...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Yang, Xiaorong, Zhang, Hongmei, Wu, Jinzi, Yin, Litian, Yan, Liang-Jun, Zhang, Ce
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213259/
https://ncbi.nlm.nih.gov/pubmed/30274308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19102982
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