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Intracellular displacement of p53 using transactivation domain (p53 TAD) specific nanobodies
The tumor suppressor p53 is of crucial importance in the prevention of cellular transformation. In the presence of cellular stress signals, the negative feedback loop between p53 and Mdm2, its main negative regulator, is disrupted, which results in the activation and stabilization of p53. Via a comp...
Shranjeno v:
| izdano v: | MAbs |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204812/ https://ncbi.nlm.nih.gov/pubmed/30111239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1502025 |
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