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A nanobody modulates the p53 transcriptional program without perturbing its functional architecture
The p53 transcription factor plays an important role in genome integrity. To perform this task, p53 regulates the transcription of genes promoting various cellular outcomes including cell cycle arrest, apoptosis or senescence. The precise regulation of this activity remains elusive as numerous mecha...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227789/ https://ncbi.nlm.nih.gov/pubmed/25324313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku962 |
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