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Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli

The widespread use of monoclonal antibodies (mAbs) as a platform for therapeutic drug development in the pharmaceutical industry has led to an increased interest in robust experimental approaches for assessment of mAb structure, stability and dynamics. The ability to enrich proteins with stable isot...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Reddy, Prasad T., Brinson, Robert G., Hoopes, J. Todd, McClung, Colleen, Ke, Na, Kashi, Lila, Berkmen, Mehmet, Kelman, Zvi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204800/
https://ncbi.nlm.nih.gov/pubmed/30060704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1496879
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