Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes

Mycobacterium tuberculosis causes persistent infection due to its ability to evade host immune responses. M. tuberculosis induces Toll-like receptor 2 (TLR2) signaling, which influences immune responses to M. tuberculosis. TLR2 agonists expressed by M. tuberculosis include lipoproteins (e.g., LprG),...

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Publicado en:Infect Immun
Autores principales: Shukla, Supriya, Richardson, Edward T., Drage, Michael G., Boom, W. Henry, Harding, Clifford V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204744/
https://ncbi.nlm.nih.gov/pubmed/30037791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00450-18
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