Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness

It is widely recognized that airway inflammation and remodeling play a key role not only in the central airway but also small airway pathology during asthma. Nociceptin/Orphanin FQ (N/OFQ), an endogenous peptide, and its receptor N/OFQ peptide (NOP) are involved in airway hyperresponsiveness (AHR)....

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Tartaglione, Gioia, Spaziano, Giuseppe, Sgambato, Manuela, Russo, Teresa Palmira, Liparulo, Angela, Esposito, Renata, Mirra, Salvatore, Filosa, Rosanna, Roviezzo, Fiorentina, Polverino, Francesca, D'Agostino, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204362/
https://ncbi.nlm.nih.gov/pubmed/30370666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13906
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