Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma

BACKGROUND AND PURPOSE: There is evidence supporting a role for the nociceptin/orphanin FQ (N/OFQ; NOP) receptor and its endogenous ligand N/OFQ in the modulation of neurogenic inflammation, airway tone and calibre. We hypothesized that NOP receptor activation has beneficial effects upon asthma immu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Singh, Shailendra R, Sullo, Nikol, Matteis, Maria, Spaziano, Giuseppe, McDonald, John, Saunders, Ruth, Woodman, Lucy, Urbanek, Konrad, De Angelis, Antonella, De Palma, Raffaele, Berair, Rachid, Pancholi, Mitesh, Mistry, Vijay, Rossi, Francesco, Guerrini, Remo, Calò, Girolamo, D'Agostino, Bruno, Brightling, Christopher E, Lambert, David G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940820/
https://ncbi.nlm.nih.gov/pubmed/26756419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13416
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados