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An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer
BACKGROUND: Interleukin 13 receptor α2 (IL13Rα2) is overexpressed in metastatic colorectal cancer. Here, we have developed novel strategies to block IL-13 binding to IL13Rα2 in order to reduce metastatic spread. METHODS: Synthetic IL13Rα2 D1 peptide (GSETWKTIITKN) was tested for the inhibition of IL...
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| Publicado en: | Br J Cancer |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6203792/ https://ncbi.nlm.nih.gov/pubmed/30318506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0259-7 |
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