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Inhibition of Liver Metastasis in Colorectal Cancer by Targeting IL-13/IL13Rα2 Binding Site with Specific Monoclonal Antibodies

SIMPLE SUMMARY: IL13Rα2 has been repeatedly reported as an excellent therapeutic target for multiple types of advanced cancers. However, previous IL13Rα2 targeting attempts have been mostly unsuccessful. Here, we describe a novel strategy based on the blocking of the IL-13 tumorigenic activity using...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Jaén, Marta, Bartolomé, Rubén A., Aizpurua, Carmen, Martin-Regalado, Ángela, Imbaud, J. Ignacio, Casal, J. Ignacio
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038733/
https://ncbi.nlm.nih.gov/pubmed/33917458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071731
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