Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells

Background: Interleukin 13 receptor alpha 2 subunit (IL13Rα2) is overexpressed in glioblastoma (GBM), metastatic colorectal cancer (CRC) and ovarian cancer (OC). Here, we investigated the IL13Rα2 interactome searching for novel targets in cancer invasion and metastasis. Methods: The interactome of I...

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Udgivet i:Cancers (Basel)
Main Authors: Bartolomé, Rubén A., Martín-Regalado, Ángela, Jaén, Marta, Zannikou, Markella, Zhang, Peng, de los Ríos, Vivian, Balyasnikova, Irina V., Casal, J. Ignacio
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072372/
https://ncbi.nlm.nih.gov/pubmed/32098194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020500
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