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Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death

The mitogen-activated protein kinase (MAPK) pathway has been shown to be involved in both neurodevelopment and neurodegeneration. c-Jun N-terminal kinase (JNK), a MAPK important in retinal development and after optic nerve crush injury, is regulated by two upstream kinases: MKK4 and MKK7. The specif...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Syc-Mazurek, Stephanie B., Rausch, Rebecca L., Fernandes, Kimberly A., Wilson, Michael P., Libby, Richard T.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203745/
https://ncbi.nlm.nih.gov/pubmed/30367030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1079-7
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