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A TIAM double hit to oppose YAP/TAZ
In this issue of Cancer Cell, Diamantopoulou et al. uncover dual mechanisms of inhibiting YAP/TZ by TIAM1 that oppose invasiveness of colorectal cancer cells: TIAM1 interacts with TAZ in the cytoplasm to promote TAZ degradation by the destruction complex, whereas it antagonizes binding of TAZ/YAP to...
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| Vydáno v: | Cancer Cell |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6203307/ https://ncbi.nlm.nih.gov/pubmed/28486099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.04.009 |
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