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Physiological cyclic hydrostatic pressure induces osteogenic lineage commitment of human bone marrow stem cells: a systematic study

BACKGROUND: Physical loading is necessary to maintain bone tissue integrity. Loading-induced fluid shear is recognised as one of the most potent bone micromechanical cues and has been shown to direct stem cell osteogenesis. However, the effect of pressure transients, which drive fluid flow, on human...

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Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Stavenschi, Elena, Corrigan, Michele A., Johnson, Gillian P., Riffault, Mathieu, Hoey, David A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203194/
https://ncbi.nlm.nih.gov/pubmed/30359324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1025-8
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