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TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium

Skeletal homeostasis requires the continued replenishment of the bone forming osteoblast from a mesenchymal stem cell (MSC) population, a process that has been shown to be mechanically regulated. However, the mechanisms by which a biophysical stimulus can induce a change in biochemical signaling, me...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Corrigan, Michele A., Johnson, Gillian P., Stavenschi, Elena, Riffault, Mathieu, Labour, Marie-Noelle, Hoey, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830574/
https://ncbi.nlm.nih.gov/pubmed/29491434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22174-3
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