Physiological cyclic hydrostatic pressure induces osteogenic lineage commitment of human bone marrow stem cells: a systematic study

BACKGROUND: Physical loading is necessary to maintain bone tissue integrity. Loading-induced fluid shear is recognised as one of the most potent bone micromechanical cues and has been shown to direct stem cell osteogenesis. However, the effect of pressure transients, which drive fluid flow, on human...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Stavenschi, Elena, Corrigan, Michele A., Johnson, Gillian P., Riffault, Mathieu, Hoey, David A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203194/
https://ncbi.nlm.nih.gov/pubmed/30359324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1025-8
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