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Cu(2+) selective chelators relieve copper-induced oxidative stress in vivo

Copper ions are essential for biological function yet are severely detrimental when present in excess. At the molecular level, copper ions catalyze the production of hydroxyl radicals that can irreversibly alter essential bio-molecules. Hence, selective copper chelators that can remove excess copper...

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Vydáno v:Chem Sci
Hlavní autoři: Rakshit, Ananya, Khatua, Kaustav, Shanbhag, Vinit, Comba, Peter, Datta, Ankona
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202919/
https://ncbi.nlm.nih.gov/pubmed/30450181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04041a
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