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A rationally designed peptoid for the selective chelation of Zn(2+) over Cu(2+)

The selective removal of Zn(2+) from proteins by using a synthetic chelator is a promising therapeutic approach for the treatment of various diseases including cancer. Although the chelation of Zn(2+) is well known, its removal from a protein in the presence of potential competing biologically relev...

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Publicado en:Chem Sci
Autores principales: Ghosh, Pritam, Maayan, Galia
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society of Chemistry 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162371/
https://ncbi.nlm.nih.gov/pubmed/34094275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03391j
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