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Cu(2+) selective chelators relieve copper-induced oxidative stress in vivo

Copper ions are essential for biological function yet are severely detrimental when present in excess. At the molecular level, copper ions catalyze the production of hydroxyl radicals that can irreversibly alter essential bio-molecules. Hence, selective copper chelators that can remove excess copper...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Rakshit, Ananya, Khatua, Kaustav, Shanbhag, Vinit, Comba, Peter, Datta, Ankona
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202919/
https://ncbi.nlm.nih.gov/pubmed/30450181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04041a
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