Mesenchymal stromal cells from myelodysplastic and acute myeloid leukemia patients display in vitro reduced proliferative potential and similar capacity to support leukemia cell survival

BACKGROUND: Mesenchymal stromal cells (MSCs) are an essential element of the bone marrow (BM) microenvironment, playing a crucial function in regulating hematopoietic stem cell proliferation and differentiation. Recent findings have outlined a putative role for MSCs in hematological malignancy devel...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Corradi, Giulia, Baldazzi, Carmen, Očadlíková, Darina, Marconi, Giovanni, Parisi, Sarah, Testoni, Nicoletta, Finelli, Carlo, Cavo, Michele, Curti, Antonio, Ciciarello, Marilena
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202844/
https://ncbi.nlm.nih.gov/pubmed/30359303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1013-z
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