The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia

Mesenchymal stromal cells (MSCs) have, for a long time, been recognized as pivotal contributors in the set up and maintenance of the hematopoietic stem cell (HSC) niche, as well as in the development and differentiation of the lympho-hematopoietic system. MSCs also have a unique immunomodulatory cap...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Ciciarello, Marilena, Corradi, Giulia, Loscocco, Federica, Visani, Giuseppe, Monaco, Federica, Cavo, Michele, Curti, Antonio, Isidori, Alessandro
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823864/
https://ncbi.nlm.nih.gov/pubmed/31709192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01135
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