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A Regression Approach to Visual Predictive Checks for Population Pharmacometric Models

A visual predictive check (VPC) is a common diagnostic procedure for population pharmacometric models. Typically, VPCs are generated by specifying intervals, or “bins”, of an independent variable (e.g., time). However, bin specification is not always straightforward and the choice of bins may affect...

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Bibliographische Detailangaben
Veröffentlicht in:CPT Pharmacometrics Syst Pharmacol
Hauptverfasser: Jamsen, Kris M., Patel, Kashyap, Nieforth, Keith, Kirkpatrick, Carl M. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202468/
https://ncbi.nlm.nih.gov/pubmed/30058222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12319
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