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Visualization and Communication of Pharmacometric Models With Berkeley Madonna

Population or other pharmacometric models are a useful means to describe, succinctly, the relationships between drug administration, exposure (concentration), and downstream changes in pharmacodynamic (PD) biomarkers and clinical endpoints, including the mixed effects of patient factors and random i...

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Detalhes bibliográficos
Main Authors: Krause, A, Lowe, P J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055786/
https://ncbi.nlm.nih.gov/pubmed/24872204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.13
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