Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation

Allogeneic transplantation (allo-HCT) has led to the cure of HIV in one individual, raising the question of whether transplantation can eradicate the HIV reservoir. To test this, we here present a model of allo-HCT in SHIV-infected, cART-suppressed nonhuman primates. We infect rhesus macaques with S...

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Vydáno v:Nat Commun
Hlavní autoři: Colonna, Lucrezia, Peterson, Christopher W., Schell, John B., Carlson, Judith M., Tkachev, Victor, Brown, Melanie, Yu, Alison, Reddy, Sowmya, Obenza, Willi M., Nelson, Veronica, Polacino, Patricia S., Mack, Heather, Hu, Shiu-Lok, Zeleski, Katie, Hoffman, Michelle, Olvera, Joe, Furlan, Scott N., Zheng, Hengqi, Taraseviciute, Agne, Hunt, Daniel J., Betz, Kayla, Lane, Jennifer F., Vogel, Keith, Hotchkiss, Charlotte E., Moats, Cassie, Baldessari, Audrey, Murnane, Robert D., English, Christopher, Astley, Cliff A., Wangari, Solomon, Agricola, Brian, Ahrens, Joel, Iwayama, Naoto, May, Andrew, Stensland, Laurence, Huang, Meei-Li W., Jerome, Keith R., Kiem, Hans-Peter, Kean, Leslie S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202377/
https://ncbi.nlm.nih.gov/pubmed/30361514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06736-7
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