Novel role of Giα2 in cell migration: Downstream of PI3-kinase/AKT and Rac1 in prostate cancer cells

Tumor cell motility is the essential step in cancer metastasis. Previously we showed that oxytocin and EGF effects on cell migration in prostate cancer cells require Giα2 protein. In the present study, we investigated the interactions among GPCR, Giα2, PI3-kinase and Rac1 activation in the induction...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Physiol
Prif Awduron: Caggia, Silvia, Chunduri, HimaBindu, Millena, Ana C., Perkins, Jonathan N., Venugopal, Smrruthi V., Vo, BaoHan T., Li, Chunliang, Tu, Yaping, Khan, Shafiq A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202161/
https://ncbi.nlm.nih.gov/pubmed/30078221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26894
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