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Novel role of Giα2 in cell migration: Downstream of PI3-kinase/AKT and Rac1 in prostate cancer cells

Tumor cell motility is the essential step in cancer metastasis. Previously we showed that oxytocin and EGF effects on cell migration in prostate cancer cells require Giα2 protein. In the present study, we investigated the interactions among GPCR, Giα2, PI3-kinase and Rac1 activation in the induction...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Caggia, Silvia, Chunduri, HimaBindu, Millena, Ana C., Perkins, Jonathan N., Venugopal, Smrruthi V., Vo, BaoHan T., Li, Chunliang, Tu, Yaping, Khan, Shafiq A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202161/
https://ncbi.nlm.nih.gov/pubmed/30078221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26894
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