Genome-wide association analysis identifies SNPs predictive of in vitro leukemic cell sensitivity to cytarabine in pediatric AML

Cytarabine has been an integral part of acute myeloid leukemia (AML) chemotherapy for over four decades. However, development of resistance and high rates of relapse is a significant impediment in successfully treating AML. We performed a genome-wide association analysis (GWAS) and identified 113 (8...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Bargal, Salma A., Rafiee, Roya, Crews, Kristine R., Wu, Huiyun, Cao, Xueyuan, Rubnitz, Jeffrey E., Ribeiro, Raul C., Downing, James R., Pounds, Stanley B., Lamba, Jatinder K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2018
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201857/
https://ncbi.nlm.nih.gov/pubmed/30405880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26163
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