Coding polymorphisms in CD33 and response to gemtuzumab ozogamicin in pediatric patients with AML

Gemtuzumab ozogamicin (GO) is an anti-CD33 antibody conjugated with calicheamicin (a cytotoxic antibiotic) that is used for the treatment of acute myeloid leukemia (AML). The relationship between the CD33 expression in leukemic cells and response to GO treatment has been controversial. We studied CD...

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Main Authors: Lamba, Jatinder K., Pounds, Stanley, Cao, Xueyuan, Downing, James R., Campana, Dario, Ribeiro, Raul C., Pui, Ching-Hon, Rubnitz, Jeffrey E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659556/
https://ncbi.nlm.nih.gov/pubmed/18615103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.185
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