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SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities

Low levels of the survival of motor neuron (SMN) protein cause the neurodegenerative disease spinal muscular atrophy (SMA). SMA is a pediatric disease characterized by spinal motor neuron degeneration. SMA exhibits several levels of severity ranging from early antenatal fatality, to only mild muscul...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Dominguez, Catherine E., Cunningham, David, Chandler, Dawn S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201753/
https://ncbi.nlm.nih.gov/pubmed/28852871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-017-1835-2
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