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Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats

BACKGROUND: Renal hypoxia, implicated as crucial factor in onset and progression of chronic kidney disease, may be attributed to reduced nitric oxide because nitric oxide dilates vasculature and inhibits mitochondrial oxygen consumption. We hypothesized that chronic nitric oxide synthase inhibition...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Emans, Tonja W., Janssen, Ben J., Joles, Jaap A., Krediet, C.T. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://ncbi.nlm.nih.gov/pubmed/30371226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009501
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