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Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats

BACKGROUND: Renal hypoxia, implicated as crucial factor in onset and progression of chronic kidney disease, may be attributed to reduced nitric oxide because nitric oxide dilates vasculature and inhibits mitochondrial oxygen consumption. We hypothesized that chronic nitric oxide synthase inhibition...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Emans, Tonja W., Janssen, Ben J., Joles, Jaap A., Krediet, C.T. Paul
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://ncbi.nlm.nih.gov/pubmed/30371226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009501
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