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Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats

BACKGROUND: Renal hypoxia, implicated as crucial factor in onset and progression of chronic kidney disease, may be attributed to reduced nitric oxide because nitric oxide dilates vasculature and inhibits mitochondrial oxygen consumption. We hypothesized that chronic nitric oxide synthase inhibition...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Emans, Tonja W., Janssen, Ben J., Joles, Jaap A., Krediet, C.T. Paul
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://ncbi.nlm.nih.gov/pubmed/30371226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009501
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