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Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats

BACKGROUND: Renal hypoxia, implicated as crucial factor in onset and progression of chronic kidney disease, may be attributed to reduced nitric oxide because nitric oxide dilates vasculature and inhibits mitochondrial oxygen consumption. We hypothesized that chronic nitric oxide synthase inhibition...

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Bibliografische gegevens
Gepubliceerd in:J Am Heart Assoc
Hoofdauteurs: Emans, Tonja W., Janssen, Ben J., Joles, Jaap A., Krediet, C.T. Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://ncbi.nlm.nih.gov/pubmed/30371226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009501
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