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rSjP40 suppresses hepatic stellate cell activation by promoting microRNA‐155 expression and inhibiting STAT5 and FOXO3a expression

Activation of hepatic stellate cells (HSCs) is the central event of the evolution of hepatic fibrosis. Schistosomiasis is one of the pathogenic factors which could induce hepatic fibrosis. Previous studies have shown that recombinant Schistosoma japonicum egg antigen P40 (rSjP40) can inhibit the act...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Zhu, Dandan, Yang, Chunzhao, Shen, Pei, Chen, Liuting, Chen, Jinling, Sun, Xiaolei, Duan, Lian, Zhang, Li, Zhu, Jinhua, Duan, Yinong
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201359/
https://ncbi.nlm.nih.gov/pubmed/30091834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13819
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