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Recombinant SjP40 protein enhances p27 promoter expression in hepatic stellate cells via an E2F1-dependent mechanism

The p27 protein plays a critical role in cell cycle arrest. Our previous studies have demonstrated that recombinant P40 protein from Schistosoma japonicum (rSjP40) could induce G1 phase arrest of cell cycle. We, therefore, attempted to observe the effect of rSjP40 on p27 promoter activity in LX-2 ce...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Duan, Yinong, Lyu, Lei, Zhu, Dandan, Wang, Jianxin, Chen, Jinling, Chen, Liuting, Yang, Chunzhao, Sun, Xiaolei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522240/
https://ncbi.nlm.nih.gov/pubmed/28489573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17248
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