Recombinant SjP40 protein enhances p27 promoter expression in hepatic stellate cells via an E2F1-dependent mechanism

The p27 protein plays a critical role in cell cycle arrest. Our previous studies have demonstrated that recombinant P40 protein from Schistosoma japonicum (rSjP40) could induce G1 phase arrest of cell cycle. We, therefore, attempted to observe the effect of rSjP40 on p27 promoter activity in LX-2 ce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Duan, Yinong, Lyu, Lei, Zhu, Dandan, Wang, Jianxin, Chen, Jinling, Chen, Liuting, Yang, Chunzhao, Sun, Xiaolei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522240/
https://ncbi.nlm.nih.gov/pubmed/28489573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17248
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