Exosomal miR‐95‐5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2/8

MicroRNAs play critical roles in the pathogenesis of osteoarthritis, the most common chronic degenerative joint disease. Exosomes derived from miR‐95‐5p‐overexpressing primary chondrocytes (AC‐miR‐95‐5p) may be effective in treating osteoarthritis. Increased expression of HDAC2/8 occurs in the tissu...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Mao, Guping, Hu, Shu, Zhang, Ziji, Wu, Peihui, Zhao, Xiaoyi, Lin, Ruifu, Liao, Weiming, Kang, Yan
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201229/
https://ncbi.nlm.nih.gov/pubmed/30063117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13808
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