Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

OBJECTIVES: Aberrations in exosomal circular RNA (circRNA) expression have been identified in various human diseases. In this study, we investigated whether exosomal circRNAs could act as competing endogenous RNAs (ceRNAs) to regulate the pathological process of osteoarthritis (OA). This study aimed...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Mao, Guping, Xu, Yiyang, Long, Dianbo, Sun, Hong, Li, Hongyi, Xin, Ruobin, Zhang, Ziji, Li, Zhiwen, Yang, Zhi, Kang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278601/
https://ncbi.nlm.nih.gov/pubmed/34256841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02431-5
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