Novel Self-Assembled Micelles Based on Cholesterol-Modified Antimicrobial Peptide (DP7) for Safe and Effective Systemic Administration in Animal Models of Bacterial Infection

Owing to their broad-spectrum antibacterial properties, multitarget effects, and low drug resistance, antimicrobial peptides (AMPs) have played critical roles in the clinical therapy of drug-resistant bacterial infections. However, the potential hazard of hemolysis following systemic administration...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zhang, Rui, Wu, Fengbo, Wu, Lei, Tian, Yaomei, Zhou, Bailing, Zhang, Xueyan, Huang, Rong, Yu, Chaoheng, He, Gu, Yang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201105/
https://ncbi.nlm.nih.gov/pubmed/30201818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00368-18
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